Direct small-molecule inhibitors of KRAS: from structural insights to mechanism-based design | Nature Reviews Drug Discovery
The impact of early ADME profiling on drug discovery and development strategy - Drug Discovery World (DDW)
Covalent fragment libraries in drug discovery - ScienceDirect
PDF) Theoretical Basis, Experimental Design, and Computerized Simulation of Synergism and Antagonism in Drug Combination Studies
Drug development - Wikipedia
Automating drug discovery | Nature Reviews Drug Discovery
Covalent fragment libraries in drug discovery - ScienceDirect
Covalent fragment libraries in drug discovery - ScienceDirect
DNA-encoded chemistry: enabling the deeper sampling of chemical space | Nature Reviews Drug Discovery
CISNE: An accurate description of dose-effect and synergism in combination therapies | Scientific Reports
DeepConv-DTI: Prediction of drug-target interactions via deep learning with convolution on protein sequences
The implications of target saturation for the use of drug–target residence time | Nature Reviews Drug Discovery
Organ‐on‐chip models: Implications in drug discovery and clinical applications - Mittal - 2019 - Journal of Cellular Physiology - Wiley Online Library
Macrocycles in new drug discovery | Future Medicinal Chemistry
The nature of ligand efficiency | SpringerLink
Automating drug discovery | Nature Reviews Drug Discovery
Computational design of substrate selective inhibition
An in vitro toolbox to accelerate anti-malarial drug discovery and development | Malaria Journal | Full Text
PDF) The nature of ligand efficiency
Effects of target binding kinetics on in vivo drug efficacy: koff, kon and rebinding - Vauquelin - 2016 - British Journal of Pharmacology - Wiley Online Library
Mechanistic enzymology in drug discovery: a fresh perspective | Nature Reviews Drug Discovery
Recent advances in combinatorial drug screening and synergy scoring - ScienceDirect
Recent advances in combinatorial drug screening and synergy scoring - ScienceDirect
Application of computational methods for anticancer drug discovery, design, and optimization - ScienceDirect
IJMS | Free Full-Text | Key Topics in Molecular Docking for Drug Design | HTML
